Program

Tentative program of symposia (updated on Apr. 24, 2017)

June 22, 2017, Thursday PM 5:00-6:00

PM 3:00- 5:00 Registration
PM 5:00- 5:10 Welcome Address
Hiroshi KOBAYASHI
President of the Sapporo Cancer Seminar Foundation
PM 5:10- 6:00

OPENING LECTURE 1

Yutaka KAWAKAMI
"Overview of recent advances of tumor immunology and immunotherapy"

June 23, 2017, Friday AM 9:00-PM 7:00

AM 9:00-11:05

Session 1 Tumor antigens and vaccine adjuvants

Takayuki KANASEKI
"Landscape of the HLA class I ligand peptides"

Kazuhiro KAKIMI
"An Immunogram for the Cancer-Immunity Cycle"

Matthew M. Gubin
"Immunotherapeutic Responses to Cancer Neoantigens"
Department of Pathology and Immunology, Washington University, USA

Tsukasa SEYA
"Development of non-inflammatory adjuvant that improves dendritic cell priming and tumor microenvironment"

Ken ISHII
"Nucleic acid-based vaccine and adjuvant delivered by extracellular nano-micro-particle"

AM 11:15-12:05

KEYNOTE LECTURE 1

Esteban Celis
"Immunotherapy strategies to enhance T cell infiltration into solid tumors"
Department of Biochemistry and Molecular Biology, Georgia Cancer Center, Augusta University, USA

PM 1:15-3:25

Session 2 Tumor microenvironment

Shinichi HASHIMOTO
"Single-cell transcriptome analysis of endometrioid adenocarcinoma tissues"

Dmitry I. Gabrilovich
"Regulatory myeloid cells in cancer. New therapeutic opportunities"
Translational Tumor Immunology, The Wistar Institute, USA

Kenichiro SEINO
"A novel role of IL-34 in tumor microenvironment"

Dario Vignali, PhD
"Targeting Tregs in Tumors"
Department of Immunology, University of Pittsburgh School of Medicine, USA

PM 3:40-5:40

Session 3 Immunosurveillance and Immune checkpoint

Guido Kroemer, MD, PhD
"Natural and therapy-induced anticancer immunosurveillance"
French National Institute of Health and Medical Research (INSERM), France

Koji MATSUSHIMA
"Development of novel combination cancer immunotherapeutics with anti-CD4 depleting antibody"

Kenji CHAMOTO
"Mitochondrial manipulation improves PD-1 blockade immunotherapy"

PM 5:50-7:00 Poster Session
PM 7:15-9:00 Party

June 24, 2017, Saturday AM 9:00-PM 5:45

AM 9:00-9:50

KEYNOTE LECTURE 2

Philip D. Greenberg, MD, PhD
"Engineering T cells to effectively target and eradicate tumors"
Program in Immunology, Fred Hutchinson Cancer Research Center, University of Washington, USA

AM 10:00-12:00

Session 4 Combination immunotherapy

Weiping Zou, MD, PhD
"Cancer immunosuppressive mechanisms and PD-L1/PD-1 pathway"
Department of Surgery, Immunology and Tumor Biology, University of Michigan, USA

Hiroyoshi NISHIKAWA
"Complexity of immune suppressive microenvironment in cancers"

Shigehisa KITANO
"Strategy of Combination Immunotherapy and Immune-related Adverse Event"

PM 1:15-3:15

Session 5 Antigen-specific immunotherapy

Cornelis Melief, MD, PhD
"Combination immunotherapy of cancer caused by Human Papilloma Virus"
Department of Immunohematology & Blood Transfusion, Leiden University Medical Centre, The Netherlands

Yasuharu NISHIMURA
"A possible Th1 cell-activating combination cancer immunotherapy using active immunization and IL-6 signaling blockade"

Yoshihiko HIROHASHI
"Immunothrapeutic strategy targeting cancer-stem cells"

PM 3:30-5:35

Session 6 T-cell biology, engineering, and adoptive immunotherapy

Tomohide TSUKAHARA
"A novel population of stem-like memory T-cells"

Heiichiro UDONO
"T cell metabolism links with effector mechanism in tumor microenvironment"

Naoto Hirano, MD, PhD
"Epigenetic and genetic Modifications of antitumor T cell grafts for optimal adoptive T cell therapy"
Tumor Immunology Program, Princess Margaret Cancer Centre, Department of Immunology, University of Toronto, Canada

Koji TAMADA
"Novel technologies in gene-modified T cell therapy"

Hiroaki IKEDA
"Extended applications of cancer immunotherapy with engineered T cells"

PM 5:35-5:45 Closing Remarks
Yutaka KAWAKAMI
President of the 36th Sapporo International Cancer Symposium

June 25, 2017, Sunday

Optional excursion to Lake Toya Resort

Invited Speakers (as of Feb. 22, 2017)

Philip D. Greenberg, MD, PhD
"Engineering T cells to effectively target and eradicate tumors"

Program in Immunology, Fred Hutchinson Cancer Research Center,
University of Washington, USA

Guido Kroemer, MD, PhD
"Natural and therapy-induced anticancer immunosurveillance"

French National Institute of Health and Medical Research (INSERM), France
The Founding President of the European Academy of Tumor Immunology

Weiping Zou, MD, PhD
"Cancer immunosuppressive mechanisms and PD-L1/PD-1 pathway"

Department of Surgery, Immunology and Tumor Biology,
University of Michigan, USA

Cornelis Melief, MD, PhD
"Combination immunotherapy of cancer caused by Human Papilloma Virus"

Department of Immunohematology & Blood Transfusion,
Leiden University Medical Centre, The Netherlands

Esteban Celis, MD, PhD
"Immunotherapy strategies to enhance T cell infiltration into solid tumors"

Department of Biochemistry and Molecular Biology,
Georgia Cancer Center, Augusta University, USA

Dario Vignali, PhD
"Targeting Tregs in Tumors"

Department of Immunology,
University of Pittsburgh School of Medicine, USA

Naoto Hirano, MD, PhD
"Epigenetic and genetic Modifications of antitumor T cell grafts for optimal adoptive T cell therapy"

Tumor Immunology Program, Princess Margaret Cancer Centre,
Department of Immunology, University of Toronto, Canada

Matthew M. Gubin, PhD
"Immunotherapeutic Responses to Cancer Neoantigens"

Department of Pathology and Immunology,
Washington University, USA

Dmitry I. Gabrilovich, MD, PhD
"Regulatory myeloid cells in cancer. New therapeutic opportunities"

Translational Tumor Immunology,
The Wistar Institute, USA